Enhancement effects of martentoxin on glioma BK channel and BK channel (α+β1) subtypes.

BACKGROUND: BK channels are usually activated by membrane depolarization and cytoplasmic Ca(2+). Especially,the activity of BK channel (α+β4) can be modulated by martentoxin, a 37 residues peptide, with Ca(2+)-dependent manner. gBK channel (glioma BK channel) and BK channel (α+β1) possessed higher C...

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Bibliographic Details
Main Authors: Jie Tao, Jian Shi, Li Yan, Ying Chen, Yan Hong Duan, Pin Ye, Qi Feng, Jian Wei Zhang, Xue Qin Shu, Yong Hua Ji
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3060806?pdf=render