14-3-3 σ expression effects G2/M response to oxygen and correlates with ovarian cancer metastasis.

In vitro cell culture experiments with primary cells have reported that cell proliferation is retarded in the presence of ambient compared to physiological O₂ levels. Cancer is primarily a disease of aberrant cell proliferation, therefore, studying cancer cells grown under ambient O₂ may be undesira...

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Bibliographic Details
Main Authors: Dashnamoorthy Ravi, Yidong Chen, Bijal Karia, Adam Brown, Ting Ting Gu, Jie Li, Mark S Carey, Bryan T Hennessy, Alexander J R Bishop
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3018427?pdf=render