The mtDNA nt7778 G/T polymorphism augments formation of lymphocytic foci but does not aggravate cerulein-induced acute pancreatitis in mice.

A polymorphism in the ATP synthase 8 (ATP8) gene of the murine mitochondrial genome, G-to-T transversion at position 7778, has been suggested to increase susceptibility to multiple autoimmune diseases, including autoimmune pancreatitis (AIP). The polymorphism also induces mitochondrial reactive oxyg...

Full description

Bibliographic Details
Main Authors: Sarah Müller, Burkhard Krüger, Falko Lange, Cristin N Bock, Horst Nizze, Änne Glass, Saleh M Ibrahim, Robert Jaster
Format: Article
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access: