Distinct roles of Dlk1 isoforms in bi-potential differentiation of hepatic stem cells

Abstract Background Fully understanding the developmental process of hepatic stem cells (HSCs) and the mechanisms of their committed differentiation is essential for optimizing the generation of functional hepatocytes for cell therapy in liver disease. Delta-like 1 homolog (Dlk1), primarily the memb...

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Bibliographic Details
Main Authors: Jiefang Huang, Xiaonan Zhao, Jian Wang, Yiji Cheng, Qiong Wu, Bei Wang, Fang Zhao, Lijun Meng, Yanyun Zhang, Min Jin, Huanbai Xu
Format: Article
Language:English
Published: BMC 2019-01-01
Series:Stem Cell Research & Therapy
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13287-019-1131-2