Novel 2-Thioxanthine and Dipyrimidopyridine Derivatives: Synthesis and Antimicrobial Activity

Several fused imidazolopyrimidines were synthesized starting from 6-amino-1-methyl-2-thiouracil (1) followed by nitrosation, reduction and condensation with different aromatic aldehydes to give Schiff’s base. The dehydrocyclization of Schiff’s bases using iodine/DMF gave Compounds 5a–g. The methylat...

Full description

Bibliographic Details
Main Authors: Samar El-kalyoubi, Fatmah Agili, Shaker Youssif
Format: Article
Language:English
Published: MDPI AG 2015-10-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/20/10/19263