MHC allele frequency distributions under parasite-driven selection: A simulation model
<p>Abstract</p> <p>Background</p> <p>The extreme polymorphism that is observed in major histocompatibility complex (MHC) genes, which code for proteins involved in recognition of non-self oligopeptides, is thought to result from a pressure exerted by parasites because p...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2010-10-01
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Series: | BMC Evolutionary Biology |
Online Access: | http://www.biomedcentral.com/1471-2148/10/332 |