MHC allele frequency distributions under parasite-driven selection: A simulation model

<p>Abstract</p> <p>Background</p> <p>The extreme polymorphism that is observed in major histocompatibility complex (MHC) genes, which code for proteins involved in recognition of non-self oligopeptides, is thought to result from a pressure exerted by parasites because p...

Full description

Bibliographic Details
Main Authors: Radwan Jacek, Babik Wiesław, Ejsmond Maciej
Format: Article
Language:English
Published: BMC 2010-10-01
Series:BMC Evolutionary Biology
Online Access:http://www.biomedcentral.com/1471-2148/10/332