Increased serum calpain activity is associated with HMGB1 levels in systemic sclerosis

Increased serum calpain activity is associated with HMGB1 levels in systemic sclerosis

Abstract Background Systemic sclerosis (SSc) or scleroderma is an intractable autoimmune disorder that affects multiple organs. The objectives were to investigate clinical correlations of serum calpain activity and high mobility group box 1 (HMGB1) levels with immunological and clinical traits. Meth...

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Bibliographic Details
Main Authors: Ji-Na Zheng, Yang Li, Yue-Mei Yan, Yong Yu, Wen-Qi Shao, Qiang Wang
Format: Article
Language:English
Published: BMC 2020-05-01
Series:Arthritis Research & Therapy
Subjects:
Systemic sclerosis
Interstitial lung disease
Calpain
HMGB1
Microarray analysis
Online Access:http://link.springer.com/article/10.1186/s13075-020-02195-y

Internet

http://link.springer.com/article/10.1186/s13075-020-02195-y

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