Chloroquine and its derivatives exacerbate B19V-associated anemia by promoting viral replication.

BACKGROUND: An unexpectedly high seroprevalence and pathogenic potential of human parvovirus B19 (B19V) have been observed in certain malaria-endemic countries in parallel with local use of chloroquine (CQ) as first-line treatment for malaria. The aims of this study were to assess the effect of CQ a...

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Bibliographic Details
Main Authors: Claudia Bönsch, Christoph Kempf, Ivo Mueller, Laurens Manning, Moses Laman, Timothy M E Davis, Carlos Ros
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC2860510?pdf=render