APOE and COMT polymorphisms are complementary biomarkers of status, stability, and transitions in normal aging and early mild cognitive impairment

APOE and COMT polymorphisms are complementary biomarkers of status, stability, and transitions in normal aging and early mild cognitive impairment

Objective: Research has reported associations among selected genetic susceptibility biomarkers and risk of (a) normal cognitive aging decrements, (b) established mild cognitive impairment (MCI), and (c) sporadic Alzheimer’s disease (AD). In focusing on the transitional normal-to-early MCI phase, we...

Full description

Bibliographic Details
Main Authors: Roger A Dixon, Correne A DeCarlo, Stuart W.S. MacDonald, David eVergote, Jack eJhamandas, David eWestaway
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-09-01
Series:Frontiers in Aging Neuroscience
Subjects:
Apolipoproteins E
Mild Cognitive Impairment
COMT Val158Met polymorphism
BDNF Val66Met
Victoria Longitudinal Study
Impairment Stability
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnagi.2014.00236/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnagi.2014.00236/full

Similar Items