Subcellular storage and release mode of the novel 18F-labeled sympathetic nerve PET tracer LMI1195

Subcellular storage and release mode of the novel 18F-labeled sympathetic nerve PET tracer LMI1195

Abstract Background 18F-N-[3-bromo-4-(3-fluoro-propoxy)-benzyl]-guanidine (18F-LMI1195) is a new class of PET tracer designed for sympathetic nervous imaging of the heart. The favorable image quality with high and specific neural uptake has been previously demonstrated in animals and humans, but int...

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Bibliographic Details
Main Authors: Xinyu Chen, Rudolf A. Werner, Constantin Lapa, Naoko Nose, Mitsuru Hirano, Mehrbod S. Javadi, Simon Robinson, Takahiro Higuchi
Format: Article
Language:English
Published: SpringerOpen 2018-02-01
Series:EJNMMI Research
Subjects:
Heart failure
Sympathetic nervous system
Storage vesicle turnover
Positron emission tomography
18F-LMI1195
Phaeochromocytoma
Online Access:http://link.springer.com/article/10.1186/s13550-018-0365-9

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http://link.springer.com/article/10.1186/s13550-018-0365-9

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