The Complex Function of Hsp70 in Metastatic Cancer
Elevated expression of the inducible heat shock protein 70 (Hsp70) is known to correlate with poor prognosis in many cancers. Hsp70 confers survival advantage as well as resistance to chemotherapeutic agents, and promotes tumor cell invasion. At the same time, tumor-derived extracellular Hsp70 has b...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2013-12-01
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Series: | Cancers |
Subjects: | |
Online Access: | http://www.mdpi.com/2072-6694/6/1/42 |