Macrophage galactose-type lectin (MGL) is induced on M2 microglia and participates in the resolution phase of autoimmune neuroinflammation

Macrophage galactose-type lectin (MGL) is induced on M2 microglia and participates in the resolution phase of autoimmune neuroinflammation

Abstract Background Multiple sclerosis (MS) involves a misdirected immune attack against myelin in the brain and spinal cord, leading to profound neuroinflammation and neurodegeneration. While the mechanisms of disease pathogenesis have been widely studied, the suppression mechanisms that lead to th...

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Bibliographic Details
Main Authors: Juan M. Ilarregui, Gijs Kooij, Ernesto Rodríguez, Susanne M. A. van der Pol, Nathalie Koning, Hakan Kalay, Joost C. van der Horst, Sandra J. van Vliet, Juan J. García-Vallejo, Helga E. de Vries, Yvette van Kooyk
Format: Article
Language:English
Published: BMC 2019-06-01
Series:Journal of Neuroinflammation
Subjects:
C-type lectin receptors
MGL
Multiple sclerosis
Experimental autoimmune encephalomyelitis
Microglia
Inflammation
Online Access:http://link.springer.com/article/10.1186/s12974-019-1522-4

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http://link.springer.com/article/10.1186/s12974-019-1522-4

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