Cysteine [2,4] Disulfide Bond as a New Modifiable Site of α-Conotoxin TxIB

α-Conotoxin TxIB, a selective antagonist of α6/α3β2β3 nicotinic acetylcholine receptor, could be a potential therapeutic agent for addiction and Parkinson’s disease. As a peptide with a complex pharmacophoric conformation, it is important and difficult to find a modifiable site which can be modified...

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Bibliographic Details
Main Authors: Baojian Zhang, Maomao Ren, Yang Xiong, Haonan Li, Yong Wu, Ying Fu, Dongting Zhangsun, Shuai Dong, Sulan Luo
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Marine Drugs
Subjects:
Online Access:https://www.mdpi.com/1660-3397/19/2/119