A comprehensive association analysis of homocysteine metabolic pathway genes in Singaporean Chinese with ischemic stroke.

BACKGROUND: The effect of genetic factors, apart from 5,10-methylenetetrahydrofolate reductase (MTHFR) polymorphisms, on elevated plasma homocysteine levels and increasing ischemic stroke risk have not been fully elucidated. We conducted a comprehensive analysis of 25 genes involved in homocysteine...

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Main Authors: Hui-Qi Low, Christopher P L H Chen, Katherine Kasiman, Anbupalam Thalamuthu, Seok-Shin Ng, Jia-Nee Foo, Hui-Meng Chang, Meng-Cheong Wong, E-Shyong Tai, Jianjun Liu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3174208?pdf=render