Melatonin Attenuates Chromium (VI)-Induced Spermatogonial Stem Cell/Progenitor Mitophagy by Restoration of METTL3-Mediated RNA N6-Methyladenosine Modification

Melatonin Attenuates Chromium (VI)-Induced Spermatogonial Stem Cell/Progenitor Mitophagy by Restoration of METTL3-Mediated RNA N6-Methyladenosine Modification

Spermatogonial stem cells (SSCs) are the basis of spermatogenesis, and any damage to SSCs may result in spermatogenic disorder and male infertility. Chromium (Cr) (VI) is a proven toxin, mutagen, and carcinogen, perpetually detrimental to environmental organisms due to its intricate and enduring det...

Full description

Bibliographic Details
Main Authors: Yinghua Lv, Tianjiao Li, Manman Yang, Lihong Su, Zhendong Zhu, Sihang Zhao, Wenxian Zeng, Yi Zheng
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
chromium (VI)
spermatogonial stem cells
mitophagy
melatonin
RNA m6A modification
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.684398/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2021.684398/full

Similar Items