Correlation between blood telomere length and CD4+ CD8+ T-cell subsets changes 96 weeks after initiation of antiretroviral therapy in HIV-1-positive individuals.

Correlation between blood telomere length and CD4+ CD8+ T-cell subsets changes 96 weeks after initiation of antiretroviral therapy in HIV-1-positive individuals.

In 31 participants who started first-line antiretroviral therapy in the NEAT 001/ANRS 143 clinical trial, we found after 96 weeks a statistically significant increase in blood telomere length (TL) of 0.04 (T/S Ratio) (p = 0.03). This increase was positively correlated with both the change in the per...

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Bibliographic Details
Main Authors: Mathieu Chalouni, Javier Rodriguez-Centeno, Assia Samri, Julian Blanco, Natalia Stella-Ascariz, Cedrick Wallet, Hernando Knobel, David Zucman, Belen Alejos Ferreras, Brigitte Autran, Rodolphe Thiebaut, François Raffi, Jose Ramon Arribas, NEAT 001/ANRS 143 Trial Study Group
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0230772

Internet

https://doi.org/10.1371/journal.pone.0230772

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