Plasmodium falciparum malaria elicits inflammatory responses that dysregulate placental amino acid transport.

Plasmodium falciparum malaria elicits inflammatory responses that dysregulate placental amino acid transport.

Placental malaria (PM) can lead to poor neonatal outcomes, including low birthweight due to fetal growth restriction (FGR), especially when associated with local inflammation (intervillositis or IV). The pathogenesis of PM-associated FGR is largely unknown, but in idiopathic FGR, impaired transplace...

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Bibliographic Details
Main Authors: Philippe Boeuf, Elizabeth H Aitken, Upeksha Chandrasiri, Caroline Lin Lin Chua, Bernie McInerney, Leon McQuade, Michael Duffy, Malcolm Molyneux, Graham Brown, Jocelyn Glazier, Stephen J Rogerson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-02-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3567154?pdf=render

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http://europepmc.org/articles/PMC3567154?pdf=render

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