LncRNA SNHG9 is downregulated in osteoarthritis and inhibits chondrocyte apoptosis by downregulating miR-34a through methylation

LncRNA SNHG9 is downregulated in osteoarthritis and inhibits chondrocyte apoptosis by downregulating miR-34a through methylation

Abstract Background Our preliminary RNA-Seq data revealed altered expression of small nucleolar RNA host gene 9 (SNHG9) in osteoarthritis (OA) and its reverse correlation with miR-34a, which can regulate chondrocyte apoptosis in rat OA model. This study was therefore carried out to investigate the p...

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Bibliographic Details
Main Authors: Hongfei Zhang, Jinglian Li, Weiguang Shao, Naipeng Shen
Format: Article
Language:English
Published: BMC 2020-08-01
Series:BMC Musculoskeletal Disorders
Subjects:
Osteoarthritis
SNHG9
miR-34a
Chondrocytes
Methylation
Online Access:http://link.springer.com/article/10.1186/s12891-020-03497-7

Internet

http://link.springer.com/article/10.1186/s12891-020-03497-7

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