Differential ABC transporter gene expression in adult Dirofilaria immitis males and females following in vitro treatment with ivermectin, doxycycline or a combination of both

Differential ABC transporter gene expression in adult Dirofilaria immitis males and females following in vitro treatment with ivermectin, doxycycline or a combination of both

Abstract Background Combination doxycycline/macrocyclic lactone (ML) protocols have been shown to provide a more rapid adulticidal and microfilaricidal effect than either MLs or doxycycline alone, although female worms were reported to have a higher tolerance to treatments compared to male worms. Th...

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Bibliographic Details
Main Authors: Chiara Lucchetti, Marco Genchi, Luigi Venco, Alessandro Menozzi, Paolo Serventi, Simone Bertini, Chiara Bazzocchi, Laura Helen Kramer, Alice Vismarra
Format: Article
Language:English
Published: BMC 2019-08-01
Series:Parasites & Vectors
Subjects:
Dirofilaria immitis
PgP
Gene expression
Doxycycline
Ivermectin
Combined treatment
Online Access:http://link.springer.com/article/10.1186/s13071-019-3645-y

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http://link.springer.com/article/10.1186/s13071-019-3645-y

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