Free-living human cells reconfigure their chromosomes in the evolution back to uni-cellularity

Cells of multi-cellular organisms evolve toward uni-cellularity in the form of cancer and, if humans intervene, continue to evolve in cell culture. During this process, gene dosage relationships may evolve in novel ways to cope with the new environment and may regress back to the ancestral uni-cellu...

Full description

Bibliographic Details
Main Authors: Jin Xu, Xinxin Peng, Yuxin Chen, Yuezheng Zhang, Qin Ma, Liang Liang, Ava C Carter, Xuemei Lu, Chung-I Wu
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-12-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/28070