C. elegans VANG-1 modulates life span via insulin/IGF-1-like signaling.

The planar cell polarity (PCP) pathway is highly conserved from Drosophila to humans and a PCP-like pathway has recently been described in the nematode Caenorhabditis elegans. The developmental function of this pathway is to coordinate the orientation of cells or structures within the plane of an ep...

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Bibliographic Details
Main Authors: Sebastian J Honnen, Christian Büchter, Verena Schröder, Michael Hoffmann, Yuji Kohara, Andreas Kampkötter, Olaf Bossinger
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3281126?pdf=render