Distinct Human NK Cell Phenotypes and Functional Responses to Mycobacterium tuberculosis in Adults From TB Endemic and Non-endemic Regions

Distinct Human NK Cell Phenotypes and Functional Responses to Mycobacterium tuberculosis in Adults From TB Endemic and Non-endemic Regions

Mycobacterium tuberculosis (Mtb) is the causative agent of tuberculosis (TB), which leads to an estimated 1. 5 million deaths worldwide each year. Although the immune correlates of protection against Mtb infection and TB disease have not been well-defined, natural killer (NK) cells are increasingly...

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Bibliographic Details
Main Authors: Levelle D. Harris, Jeremiah Khayumbi, Joshua Ongalo, Loren E. Sasser, Joan Tonui, Angela Campbell, Felix Hayara Odhiambo, Samuel Gurrion Ouma, Galit Alter, Neel R. Gandhi, Cheryl L. Day
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Mycobacterium tuberculosis
LTBI
NK cells
innate immunity
phenotype
Online Access:https://www.frontiersin.org/article/10.3389/fcimb.2020.00120/full

Internet

https://www.frontiersin.org/article/10.3389/fcimb.2020.00120/full

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