Using normative modelling to detect disease progression in mild cognitive impairment and Alzheimer’s disease in a cross-sectional multi-cohort study

Using normative modelling to detect disease progression in mild cognitive impairment and Alzheimer’s disease in a cross-sectional multi-cohort study

Abstract Normative modelling is an emerging method for quantifying how individuals deviate from the healthy populational pattern. Several machine learning models have been implemented to develop normative models to investigate brain disorders, including regression, support vector machines and Gaussi...

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Bibliographic Details
Main Authors: Walter H. L. Pinaya, Cristina Scarpazza, Rafael Garcia-Dias, Sandra Vieira, Lea Baecker, Pedro F da Costa, Alberto Redolfi, Giovanni B. Frisoni, Michela Pievani, Vince D. Calhoun, João R. Sato, Andrea Mechelli
Format: Article
Language:English
Published: Nature Publishing Group 2021-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-95098-0

Internet

https://doi.org/10.1038/s41598-021-95098-0

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