Effects of PPARγ ligands on TGF-β1-induced epithelial-mesenchymal transition in alveolar epithelial cells

<p>Abstract</p> <p>Background</p> <p>Transforming growth factor β1 (TGF-β1)-mediated epithelial mesenchymal transition (EMT) of alveolar epithelial cells (AEC) may contribute to lung fibrosis. Since PPARγ ligands have been shown to inhibit fibroblast activation by TGF-β...

Full description

Bibliographic Details
Main Authors: Dagher Hayat, Tan Xiahui, Hutton Craig A, Bourke Jane E
Format: Article
Language:English
Published: BMC 2010-02-01
Series:Respiratory Research
Online Access:http://respiratory-research.com/content/11/1/21