Vaccine Adjuvants in Fish Vaccines Make a Difference: Comparing Three Adjuvants (Montanide ISA763A Oil, CpG/Poly I:C Combo and VHSV Glycoprotein) Alone or in Combination Formulated with an Inactivated Whole Salmonid Alphavirus Antigen

Vaccine Adjuvants in Fish Vaccines Make a Difference: Comparing Three Adjuvants (Montanide ISA763A Oil, CpG/Poly I:C Combo and VHSV Glycoprotein) Alone or in Combination Formulated with an Inactivated Whole Salmonid Alphavirus Antigen

Most commercial vaccines offered to the aquaculture industry include inactivated antigens (Ag) formulated in oil adjuvants. Safety concerns are related to the use of oil adjuvants in multivalent vaccines for fish, since adverse side effects (e.g., adhesions) can appear. Therefore, there is a request...

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Bibliographic Details
Main Authors: Hanna L. Thim, Stéphane Villoing, Marian McLoughlin, Karen Elina Christie, Søren Grove, Petter Frost, Jorunn B. Jørgensen
Format: Article
Language:English
Published: MDPI AG 2014-03-01
Series:Vaccines
Subjects:
salmonid alphavirus
VHSV
vaccination
adjuvant
DNA vaccine
CpG
polyI:C
complement
neutralizing antibodies
Online Access:http://www.mdpi.com/2076-393X/2/2/228

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http://www.mdpi.com/2076-393X/2/2/228

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