Exosomes Derived From Human Adipose-Derived Stem Cells Inhibit Lipogenesis Involving Hedgehog Signaling Pathway

Exosomes Derived From Human Adipose-Derived Stem Cells Inhibit Lipogenesis Involving Hedgehog Signaling Pathway

Since obesity impairs wound closure and adipose-derived exosomes (ADEs) regulate wound healing in clinical applications, we hypothesized that ADEs may inhibit adipogenesis of adipose-derived stem cells (ADSCs) to reduce the adverse effects of obesity on wound healing. Hedgehog (Hh) signaling has bee...

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Bibliographic Details
Main Authors: Ziwan Ji, Zhongming Cai, Shuming Gu, Yucang He, Zikai Zhang, Tian Li, Qing Wei, Jingping Wang, Chen Ke, Liqun Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
adipose-derived stem cells
adipogenic differentiation
exosomes
hedgehog signal pathway
lipogenic
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2021.734810/full

Internet

https://www.frontiersin.org/articles/10.3389/fbioe.2021.734810/full

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