Effective Sequential Combined Chemotherapy with Trifluridine/Tipiracil and Regorafenib in Human Colorectal Cancer Cells

Effective Sequential Combined Chemotherapy with Trifluridine/Tipiracil and Regorafenib in Human Colorectal Cancer Cells

Salvage chemotherapy for refractory metastatic colorectal cancer using trifluridine/tipiracil (FTD/TPI) and regorafenib has shown survival benefits. We evaluated the antitumor effects of FTD or FTD/TPI combined with regorafenib in vitro and in vivo. SW620, HCT 116, and HT-29 human colorectal cancer...

Full description

Bibliographic Details
Main Authors: Kazuaki Matsuoka, Fumio Nakagawa, Nozomu Tanaka, Hiroyuki Okabe, Kenichi Matsuo, Teiji Takechi
Format: Article
Language:English
Published: MDPI AG 2018-09-01
Series:International Journal of Molecular Sciences
Subjects:
trifluridine
tipiracil hydrochloride
TAS-102
regorafenib
colorectal cancer
Online Access:http://www.mdpi.com/1422-0067/19/10/2915

Internet

http://www.mdpi.com/1422-0067/19/10/2915

Similar Items