Active fragments from pro- and antiapoptotic BCL-2 proteins have distinct membrane behavior reflecting their functional divergence.

Active fragments from pro- and antiapoptotic BCL-2 proteins have distinct membrane behavior reflecting their functional divergence.

BACKGROUND: The BCL-2 family of proteins includes pro- and antiapoptotic members acting by controlling the permeabilization of mitochondria. Although the association of these proteins with the outer mitochondrial membrane is crucial for their function, little is known about the characteristics of th...

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Bibliographic Details
Main Authors: Yannis Guillemin, Jonathan Lopez, Diana Gimenez, Gustavo Fuertes, Juan Garcia Valero, Loïc Blum, Philippe Gonzalo, Jesùs Salgado, Agnès Girard-Egrot, Abdel Aouacheria
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2816717?pdf=render

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http://europepmc.org/articles/PMC2816717?pdf=render

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