Neuroprotective Function of High Glycolytic Activity in Astrocytes: Common Roles in Stroke and Neurodegenerative Diseases

Neuroprotective Function of High Glycolytic Activity in Astrocytes: Common Roles in Stroke and Neurodegenerative Diseases

Astrocytes (also, astroglia) consume huge amounts of glucose and produce lactate regardless of sufficient oxygen availability, indicating a high capacity for aerobic glycolysis. Glycolysis in astrocytes is activated in accordance with neuronal excitation and leads to increases in the release of lact...

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Bibliographic Details
Main Author: Shinichi Takahashi
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:International Journal of Molecular Sciences
Subjects:
astrocyte
astroglia
glycolysis
human induced pluripotent stem cell
lactate
pentose-phosphate pathway
Online Access:https://www.mdpi.com/1422-0067/22/12/6568

Internet

https://www.mdpi.com/1422-0067/22/12/6568

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