Polymorphisms in B Cell Co-Stimulatory Genes Are Associated with IgG Antibody Responses against Blood-Stage Proteins of Plasmodium vivax.

The development of an effective immune response can help decrease mortality from malaria and its clinical symptoms. However, this mechanism is complex and has significant inter-individual variation, most likely owing to the genetic contribution of the human host. Therefore, this study aimed to inves...

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Main Authors: Gustavo C Cassiano, Adriana A C Furini, Marcela P Capobianco, Luciane M Storti-Melo, Maristela G Cunha, Flora S Kano, Luzia H Carvalho, Irene S Soares, Sidney E Santos, Marinete M Póvoa, Ricardo L D Machado
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4763038?pdf=render