Fiber stiffness, pore size and adhesion control migratory phenotype of MDA-MB-231 cells in collagen gels.

Cancer cell migration is influenced by cellular phenotype and behavior as well as by the mechanical and chemical properties of the environment. Furthermore, many cancer cells show plasticity of their phenotype and adapt it to the properties of the environment. Here, we study the influence of fiber s...

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Bibliographic Details
Main Authors: Florian Geiger, Daniel Rüdiger, Stefan Zahler, Hanna Engelke
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0225215