trans-Caryophyllene, a Natural Sesquiterpene, Causes Tracheal Smooth Muscle Relaxation through Blockade of Voltage-Dependent Ca2+ Channels

trans-Caryophyllene, a Natural Sesquiterpene, Causes Tracheal Smooth Muscle Relaxation through Blockade of Voltage-Dependent Ca2+ Channels

trans-Caryophyllene is a major component in the essential oils of various species of medicinal plants used in popular medicine in Brazil. It belongs to the chemical class of the sesquiterpenes and has been the subject of a number of studies. Here, we evaluated the effects of this compound in airway...

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Bibliographic Details
Main Authors: Jader Santos Cruz, José Henrique Leal-Cardoso, Vania Marilande Ceccatto, Andrelina Noronha Coelho-de-Souza, Roseli Barbosa, Taylena Maria do Nascimento Garcia Teófilo, Paula Virgínia Mendes-Maia, Leidiane Pinho-da-Silva
Format: Article
Language:English
Published: MDPI AG 2012-10-01
Series:Molecules
Subjects:
trans-caryophyllene
rat tracheal smooth muscle
anti-spasmodic
voltage-dependent Ca2+ channels
Online Access:http://www.mdpi.com/1420-3049/17/10/11965

Internet

http://www.mdpi.com/1420-3049/17/10/11965

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