Isosteviol Sodium Protects against Ischemic Stroke by Modulating Microglia/Macrophage Polarization via Disruption of GAS5/miR-146a-5p sponge

Isosteviol Sodium Protects against Ischemic Stroke by Modulating Microglia/Macrophage Polarization via Disruption of GAS5/miR-146a-5p sponge

Abstract Recent studies have shown that transforming microglia phenotype from pro-inflammation of M1 phenotype to anti-inflammation and tissue-repairing M2 phenotype may be an effective therapeutic strategy for preventing ischemic stroke brain injury. Isosteviol Sodium (STV-Na) has shown promise as...

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Bibliographic Details
Main Authors: Hao Zhang, Minyi Lu, Xiaofeng Zhang, Yihe Kuai, Ying Mei, Qiwen Tan, Kailun Zhong, Xiaoou Sun, Wen Tan
Format: Article
Language:English
Published: Nature Publishing Group 2019-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-019-48759-0

Internet

https://doi.org/10.1038/s41598-019-48759-0

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