Population pharmacokinetics of artesunate and dihydroartemisinin following single- and multiple-dosing of oral artesunate in healthy subjects

<p>Abstract</p> <p>Background</p> <p>The population pharmacokinetics of artesunate (AS) and its active metabolite dihydroartemisinin (DHA) were studied in healthy subjects receiving single- or multiple-dosing of AS orally either in combination with pyronaridine (PYR) or...

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Bibliographic Details
Main Authors: Kirsch Lee E, Yu Kyung-Sang, Jang In-Jin, Naik Himanshu, Tan Beesan, Shin Chang-Sik, Craft J, Fleckenstein Lawrence
Format: Article
Language:English
Published: BMC 2009-12-01
Series:Malaria Journal
Online Access:http://www.malariajournal.com/content/8/1/304