Disturbed Presynaptic Ca2+ Signaling in Photoreceptors in the EAE Mouse Model of Multiple Sclerosis

Disturbed Presynaptic Ca2+ Signaling in Photoreceptors in the EAE Mouse Model of Multiple Sclerosis

Summary: Multiple sclerosis (MS) is a demyelinating disease caused by an auto-reactive immune system. Recent studies also demonstrated synapse dysfunctions in MS patients and MS mouse models. We previously observed decreased synaptic vesicle exocytosis in photoreceptor synapses in the EAE mouse mode...

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Bibliographic Details
Main Authors: Amrita Mukherjee, Rashmi Katiyar, Ekta Dembla, Mayur Dembla, Praveen Kumar, Anouar Belkacemi, Martin Jung, Andreas Beck, Veit Flockerzi, Karin Schwarz, Frank Schmitz
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:iScience
Subjects:
Biological Sciences
Molecular Biology
Neuroscience
Molecular Neuroscience
Cellular Neuroscience
Cell Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004220310270

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http://www.sciencedirect.com/science/article/pii/S2589004220310270

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