In-silico molecular design of heterocyclic benzimidazole scaffolds as prospective anticancer agents

In-silico molecular design of heterocyclic benzimidazole scaffolds as prospective anticancer agents

Abstract Benzimidazole is a valuable pharmacophore in the field of medicinal chemistry and exhibit wide spectrum of biological activity. Molecular docking technique is routinely used in modern drug discovery for understanding the drug-receptor interaction. The selected data set of synthesized benzim...

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Bibliographic Details
Main Authors: Sumit Tahlan, Sanjiv Kumar, Kalavathy Ramasamy, Siong Meng Lim, Syed Adnan Ali Shah, Vasudevan Mani, Balasubramanian Narasimhan
Format: Article
Language:English
Published: BMC 2019-07-01
Series:BMC Chemistry
Subjects:
Benzimidazoles
Anticancer activity
Docking
CDK-8
ER-alpha
ADME
Online Access:http://link.springer.com/article/10.1186/s13065-019-0608-5

Internet

http://link.springer.com/article/10.1186/s13065-019-0608-5

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