SREBP-1c Gene Silencing can Decrease Lipid Deposits in Bovine Hepatocytes Cultured in Vitro

Background: Fatty liver is a major metabolic disorder that occurs during early lactation in high-producing dairy cows. Sterol regulatory element-binding protein-1c (SREBP-1c) is an important transcription factor that regulates lipid synthesis by regulating the expression of lipid metabolism genes. M...

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Bibliographic Details
Main Authors: Qinghua Deng, Xinwei Li, Shixin Fu, Liheng Yin, Yuming Zhang, Tingting Wang, Jianguo Wang, Lei Liu, Xue Yuan, Guoquan Sun, Zhe Wang, Guowen Liu, Xiaobing Li
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2014-05-01
Series:Cellular Physiology and Biochemistry
Subjects:
Online Access:http://www.karger.com/Article/FullText/358720