Identification of a Region in the Common Amino-terminal Domain of Hendra Virus P, V, and W Proteins Responsible for Phase Transition and Amyloid Formation

Identification of a Region in the Common Amino-terminal Domain of Hendra Virus P, V, and W Proteins Responsible for Phase Transition and Amyloid Formation

Henipaviruses are BSL-4 zoonotic pathogens responsible in humans for severe encephalitis. Their V protein is a key player in the evasion of the host innate immune response. We previously showed that the <i>Henipavirus</i> V proteins consist of a long intrinsically disordered N-terminal d...

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Bibliographic Details
Main Authors: Edoardo Salladini, Frank Gondelaud, Juliet F. Nilsson, Giulia Pesce, Christophe Bignon, Maria Grazia Murrali, Roxane Fabre, Roberta Pierattelli, Andrey V. Kajava, Branka Horvat, Denis Gerlier, Cyrille Mathieu, Sonia Longhi
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Biomolecules
Subjects:
Hendra virus
V protein
intrinsically disordered proteins
amyloids
fibrils
phase separation and transitions
Online Access:https://www.mdpi.com/2218-273X/11/9/1324

Internet

https://www.mdpi.com/2218-273X/11/9/1324

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