Reduced synaptic function of Kainate receptors in the insular cortex of Fmr1 Knock-out mice
Abstract Fragile X syndrome is caused by the loss of fragile X mental retardation protein (FMRP). Kainate receptor (KAR) is a subfamily of ionotropic glutamate receptors (iGluR) that acts mainly as a neuromodulator of synaptic transmission and neuronal excitability. However, little is known about th...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2018-09-01
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Series: | Molecular Brain |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s13041-018-0396-1 |