Oxidative Stress in Autistic Children Alters Erythrocyte Shape in the Absence of Quantitative Protein Alterations and of Loss of Membrane Phospholipid Asymmetry

Red blood cells (RBCs) from people affected by autism spectrum disorders (ASDs) are a target of oxidative stress. By scanning electron microscopy, we analyzed RBC morphology from 22 ASD children and show here that only 47.5 ± 3.33% of RBC displayed the typical biconcave shape, as opposed to 87.5 ± 1...

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Bibliographic Details
Main Authors: Alessandra Bolotta, Michela Battistelli, Elisabetta Falcieri, Alessandro Ghezzo, Maria Cristina Manara, Stefano Manfredini, Marina Marini, Annio Posar, Paola Visconti, Provvidenza Maria Abruzzo
Format: Article
Language:English
Published: Hindawi Limited 2018-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2018/6430601