Mutations in <it>APC</it>, <it>CTNNB1 </it>and <it>K-ras </it>genes and expression of hMLH1 in sporadic colorectal carcinomas from the Netherlands Cohort Study
<p>Abstract</p> <p>Background</p> <p>The early to intermediate stages of the majority of colorectal tumours are thought to be driven by aberrations in the Wnt (<it>APC</it>, <it>CTNNB1</it>) and Ras (<it>K-ras</it>) pathways. A smalle...
Main Authors: | , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2005-12-01
|
Series: | BMC Cancer |
Online Access: | http://www.biomedcentral.com/1471-2407/5/160 |