Mutations in <it>APC</it>, <it>CTNNB1 </it>and <it>K-ras </it>genes and expression of hMLH1 in sporadic colorectal carcinomas from the Netherlands Cohort Study

Mutations in <it>APC</it>, <it>CTNNB1 </it>and <it>K-ras </it>genes and expression of hMLH1 in sporadic colorectal carcinomas from the Netherlands Cohort Study

<p>Abstract</p> <p>Background</p> <p>The early to intermediate stages of the majority of colorectal tumours are thought to be driven by aberrations in the Wnt (<it>APC</it>, <it>CTNNB1</it>) and Ras (<it>K-ras</it>) pathways. A smalle...

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Bibliographic Details
Main Authors: de Bruïne Adriaan P, van Muijen Goos NP, Roemen Guido MJM, Saritas A Merdan, Wark Petra A, Weijenberg Matty P, Lüchtenborg Margreet, van den Brandt Piet A, de Goeij Anton FPM
Format: Article
Language:English
Published: BMC 2005-12-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/5/160

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http://www.biomedcentral.com/1471-2407/5/160

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