Synthesis of Fucose Derivatives with Thiol Motifs towards Suicide Inhibition of <i>Helicobacter pylori</i>

Synthesis of Fucose Derivatives with Thiol Motifs towards Suicide Inhibition of <i>Helicobacter pylori</i>

The syntheses of six thiol-exhibiting monosaccharides towards suicide inhibition of <i>Helicobacter pylori</i> are reported. Blood group Antigen Binding Adhesin (BabA), a bacterial membrane-bound lectin, binds to human ABO and Lewis b blood group structures displayed on the surface of ho...

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Bibliographic Details
Main Authors: Mark Reihill, Lorenzo Guazzelli, Han Remaut, Stefan Oscarson
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Molecules
Subjects:
<i>H. pylori</i>
Lewis b
fucose
suicide inhibitors
BabA
lectins
Online Access:https://www.mdpi.com/1420-3049/25/18/4281

Internet

https://www.mdpi.com/1420-3049/25/18/4281

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