Nuclear-encoded factors involved in post-transcriptional processing and modification of mitochondrial tRNAs in human disease
The human mitochondrial genome (mtDNA) encodes twenty-two tRNAs (mt-tRNAs) that are necessary for the intraorganellar translation of the thirteen mtDNA-encoded subunits of the mitochondrial respiratory chain complexes. Maturation of mt-tRNAs involves 5’ and 3’ nucleolytic excision from precursor RNA...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2015-03-01
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| Series: | Frontiers in Genetics |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fgene.2015.00079/full |