A comprehensive regional neurochemical theory in depression: a protocol for the systematic review and meta-analysis of 1H-MRS studies in major depressive disorder

A comprehensive regional neurochemical theory in depression: a protocol for the systematic review and meta-analysis of 1H-MRS studies in major depressive disorder

Abstract Background Magnetic resonance spectroscopy (MRS) is a non-invasive analytical technique that investigates the presence and concentrations of brain metabolites. In the context of major depressive disorder (MDD), MRS has revealed regional biochemical changes in GABA, glutamate, and choline ac...

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Bibliographic Details
Main Authors: Thomas Drago, Patrick W O’Regan, Ivan Welaratne, Shane Rooney, Aoife O’Callaghan, Marissa Malkit, Elena Roman, Kirk J Levins, Lauren Alexander, Denis Barry, Erik O’Hanlon, Veronica O’Keane, Darren William Roddy
Format: Article
Language:English
Published: BMC 2018-10-01
Series:Systematic Reviews
Subjects:
Magnetic resonance spectroscopy
Major depressive disorder
Systematic review
Meta-analysis
Metabolite variation
Online Access:http://link.springer.com/article/10.1186/s13643-018-0830-6

Internet

http://link.springer.com/article/10.1186/s13643-018-0830-6

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