Mycobacterium tuberculosis complex lipid virulence factors preserved in the 17,000-year-old skeleton of an extinct bison, Bison antiquus.

Mycobacterium tuberculosis complex lipid virulence factors preserved in the 17,000-year-old skeleton of an extinct bison, Bison antiquus.

Tracing the evolution of ancient diseases depends on the availability and accessibility of suitable biomarkers in archaeological specimens. DNA is potentially information-rich but it depends on a favourable environment for preservation. In the case of the major mycobacterial pathogens, Mycobacterium...

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Bibliographic Details
Main Authors: Oona Y-C Lee, Houdini H T Wu, Helen D Donoghue, Mark Spigelman, Charles L Greenblatt, Ian D Bull, Bruce M Rothschild, Larry D Martin, David E Minnikin, Gurdyal S Besra
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3408397?pdf=render

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http://europepmc.org/articles/PMC3408397?pdf=render

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