Investigation of parameters that affect the success rate of microarray-based allele-specific hybridization assays.

BACKGROUND: The development of microarray-based genetic tests for diseases that are caused by known mutations is becoming increasingly important. The key obstacle to developing functional genotyping assays is that such mutations need to be genotyped regardless of their location in genomic regions. T...

Full description

Bibliographic Details
Main Authors: Lena Poulsen, Martin Jensen Søe, Lisbeth Birk Møller, Martin Dufva
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3062541?pdf=render