α, β-Amyrin, a pentacyclic triterpenoid from Protium heptaphyllum suppresses adipocyte differentiation accompanied by down regulation of PPARγ and C/EBPα in 3T3-L1 cells

α, β-Amyrin, a pentacyclic triterpenoid from Protium heptaphyllum suppresses adipocyte differentiation accompanied by down regulation of PPARγ and C/EBPα in 3T3-L1 cells

Previous studies have reported the anti-obesity effects of α, β-Amyrin in high fat-fed mice. This study aimed to evaluate whether α, β-Amyrin has an anti-adipogenic effect in 3T3-L1 murine adipocytes and to explore the possible underlying mechanisms. 3T3-L1 pre-adipocytes were differentiated in a me...

Full description

Bibliographic Details
Main Authors: Karina Moura de Melo, Francisca Tuelly Bandeira de Oliveira, Rose Anny Costa Silva, Ana Luiza Gomes Quinderé, José Delano Barreto Marinho Filho, Ana Jérsia Araújo, Eanes Delgado Barros Pereira, Adonias Almeida Carvalho, Mariana Helena Chaves, Vietla Satyanarayana Rao, Flávia Almeida Santos
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:Biomedicine & Pharmacotherapy
Subjects:
α, β-Amyrin
3T3-L1 cells
Adipocyte differentiation
PPARγ
C/EBPα
GLUT4
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332218338654

Internet

http://www.sciencedirect.com/science/article/pii/S0753332218338654

Similar Items