Imiquimod induces apoptosis of squamous cell carcinoma (SCC) cells via regulation of A20.

Imiquimod induces apoptosis of squamous cell carcinoma (SCC) cells via regulation of A20.

Imiquimod, a nucleoside analogue of the imidazoquinoline family, is being used to treat various cutaneous cancers including squamous cell carcinoma (SCC). Imiquimod activates anti-tumor immunity via Toll-like receptor 7 (TLR7) in macrophage and other immune cells. Imiquimod can also affect tumor cel...

Full description

Bibliographic Details
Main Authors: Kyung-Cheol Sohn, Zheng Jun Li, Dae-Kyoung Choi, Tiejun Zhang, Jae Woo Lim, In-Kyu Chang, Gang Min Hur, Myung Im, Young Lee, Young-Joon Seo, Jeung-Hoon Lee, Chang Deok Kim
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3990708?pdf=render

Internet

http://europepmc.org/articles/PMC3990708?pdf=render

Similar Items