Transcript Levels of Aldo-Keto Reductase Family 1 Subfamily C (AKR1C) Are Increased in Prostate Tissue of Patients with Type 2 Diabetes

Transcript Levels of Aldo-Keto Reductase Family 1 Subfamily C (AKR1C) Are Increased in Prostate Tissue of Patients with Type 2 Diabetes

Aldo-keto reductase family 1 (AKR1) enzymes play a crucial role in diabetic complications. Since type 2 diabetes (T2D) is associated with cancer progression, we investigated the impact of diabetes on <i>AKR1</i> gene expression in the context of prostate cancer (PCa) development. In this...

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Bibliographic Details
Main Authors: Andras Franko, Lucia Berti, Jörg Hennenlotter, Steffen Rausch, Marcus O. Scharpf, Martin Hrabĕ de Angelis, Arnulf Stenzl, Andreas L. Birkenfeld, Andreas Peter, Stefan Z. Lutz, Hans-Ulrich Häring, Martin Heni
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Journal of Personalized Medicine
Subjects:
prostate cancer
diabetes
aldo-keto reductase family 1
HIF1a
NFkB
Online Access:https://www.mdpi.com/2075-4426/10/3/124

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https://www.mdpi.com/2075-4426/10/3/124

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