KCML: a machine‐learning framework for inference of multi‐scale gene functions from genetic perturbation screens

Abstract Characterising context‐dependent gene functions is crucial for understanding the genetic bases of health and disease. To date, inference of gene functions from large‐scale genetic perturbation screens is based on ad hoc analysis pipelines involving unsupervised clustering and functional enr...

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Bibliographic Details
Main Authors: Heba Z Sailem, Jens Rittscher, Lucas Pelkmans
Format: Article
Language:English
Published: Wiley 2020-03-01
Series:Molecular Systems Biology
Subjects:
Online Access:https://doi.org/10.15252/msb.20199083